| 2022 Section VI Final Regular Season Standings | ||||||||||||||
| ECIC I | W | L | W | L | NIAGARA FRONTIER LEAGUE | W | L | W | L | CHARTER SCHOOLS | W | L | W | L |
| Jamestown | 13 | 1 | 17 | 3 | Niagara Wheatfield | 16 | 0 | 18 | 2 | Health Sciences | 6 | 0 | 16 | 4 |
| Orchard Park | 12 | 2 | 18 | 2 | Niagara Falls | 13 | 3 | 15 | 5 | Tapestry | 4 | 2 | 12 | 8 |
| Hamburg | 7 | 7 | 12 | 8 | Charter School For Applied Tech | 11 | 5 | 13 | 6 | WNY Maritime | 2 | 4 | 3 | 12 |
| Clarence | 7 | 7 | 11 | 9 | Lewiston-Porter | 10 | 6 | 12 | 8 | Buffalo Academy ff Science | 0 | 6 | 0 | 19 |
| Frontier | 7 | 7 | 10 | 10 | Lockport | 8 | 8 | 10 | 10 | |||||
| Lancaster | 7 | 7 | 8 | 12 | Kenmore West | 6 | 10 | 9 | 11 | CCAA WEST I | W | L | W | L |
| Williamsville North | 3 | 11 | 7 | 13 | North Tonawanda | 5 | 11 | 8 | 12 | Olean | 10 | 0 | 18 | 2 |
| West Seneca West | 0 | 14 | 2 | 18 | Kenmore East | 3 | 13 | 3 | 17 | Allegany-Limestone | 6 | 4 | 13 | 7 |
| Grand Island | 0 | 16 | 4 | 16 | Salamanca | 5 | 5 | 13 | 7 | |||||
| ECIC II | W | L | W | L | Southwestern | 5 | 5 | 8 | 12 | |||||
| Amherst | 11 | 1 | 18 | 2 | NIAGARA ORLEANS | W | L | W | L | Fredonia | 4 | 6 | 12 | 8 |
| Williamsville East | 11 | 1 | 16 | 4 | Royalton-Hartland | 10 | 2 | 12 | 7 | Dunkirk | 0 | 10 | 7 | 13 |
| Sweet Home | 7 | 5 | 11 | 9 | Newfane | 9 | 3 | 14 | 6 | |||||
| Iroquois | 6 | 6 | 12 | 8 | Medina | 6 | 6 | 7 | 11 | CCAA WEST II | W | L | W | L |
| Williamsville South | 5 | 7 | 10 | 9 | Wilson | 5 | 7 | 7 | 13 | Westfield | 12 | 0 | 19 | 1 |
| West Seneca East | 1 | 11 | 3 | 17 | Barker | 4 | 8 | 6 | 12 | Clymer | 10 | 2 | 16 | 2 |
| Starpoint | 1 | 11 | 2 | 18 | Albion | 5 | 7 | 6 | 12 | Panama | 7 | 5 | 11 | 6 |
| Akron | 3 | 9 | 6 | 14 | Sherman | 7 | 5 | 9 | 8 | |||||
| ECIC III | W | L | W | L | Chautauqua Lake | 4 | 8 | 6 | 13 | |||||
| Pioneer | 10 | 2 | 14 | 5 | YALE CUP I | W | L | W | L | Falconer | 2 | 10 | 4 | 16 |
| Depew | 9 | 3 | 14 | 6 | Mckinley | 11 | 1 | 17 | 2 | Brocton | 0 | 12 | 0 | 19 |
| East Aurora | 7 | 5 | 9 | 11 | Hutch Tech | 9 | 3 | 11 | 7 | |||||
| Maryvale | 6 | 6 | 9 | 11 | South Park | 8 | 4 | 10 | 10 | CCAA CENTRAL | W | L | W | L |
| Cheektowaga | 6 | 6 | 7 | 13 | East | 5 | 7 | 6 | 14 | Randolph | 12 | 0 | 19 | 1 |
| Lake Shore | 4 | 8 | 6 | 14 | Middle Early College | 4 | 8 | 10 | 10 | Frewsburg | 10 | 2 | 11 | 9 |
| Springville | 0 | 12 | 0 | 19 | International Prep-Da Vinci | 3 | 9 | 9 | 11 | Silver Creek | 6 | 6 | 13 | 7 |
| Bennett | 2 | 10 | 3 | 14 | Portville | 6 | 6 | 8 | 12 | |||||
| ECIC IV | W | L | W | L | Maple Grove | 4 | 8 | 8 | 10 | |||||
| Lackawanna | 12 | 0 | 16 | 4 | YALE CUP II | W | L | W | L | Cassadaga Valley | 2 | 10 | 4 | 16 |
| Holland | 9 | 3 | 15 | 5 | City Honors | 11 | 1 | 14 | 5 | Gowanda | 2 | 10 | 3 | 15 |
| Alden | 7 | 5 | 11 | 8 | Riverside-Lafayette | 10 | 2 | 15 | 3 | |||||
| Cleveland Hill | 7 | 5 | 7 | 12 | Olmsted | 8 | 4 | 13 | 5 | CCAA EAST | W | L | W | L |
| Tonawanda | 3 | 9 | 8 | 12 | Emerson | 5 | 7 | 7 | 11 | Pine Valley | 7 | 3 | 13 | 4 |
| Eden | 3 | 9 | 4 | 15 | Burgard | 4 | 8 | 10 | 10 | Ellicottville | 7 | 3 | 8 | 12 |
| JFK | 1 | 11 | 3 | 15 | Mst Seneca Prep | 3 | 9 | 5 | 13 | Cattaraugus-Little Valley | 5 | 5 | 13 | 7 |
| Buffalo Arts | 1 | 11 | 1 | 18 | Franklinville | 5 | 5 | 13 | 7 | |||||
| NON-SECTION VI SCHOOLS | W | L | W | L | North Collins | 6 | 4 | 12 | 6 | |||||
| St. Mary's School For The Deaf | 0 | 0 | 5 | 1 | SECTION VI INDEPENDENT | W | L | W | L | Forestville | 0 | 10 | 0 | 17 |
| West Seneca Christian | 0 | 0 | 4 | 7 | Global Concepts | 0 | 0 | 7 | 13 | |||||